July 1, 2020 — Melike has been promoted to Associate Professor at Penn! She is grateful to all her lab members past and present for their contributions as well as all her scientific mentors, collaborators at Penn and beyond!
Collaborative work with Mauck Lab in Science Advances
June 1, 2020 — We are thrilled to have contributed to this paper out by our close collaborators Su Chin Heo and Rob Mauck in Science Advances: https://advances.sciencemag.org/content/6/25/eaax5083.abstract
Welcome Qing!
April 1, 2020 — We welcome Qing Tang, a new postdoc in the lab who will be studying microtubule PTMs and intracellular transport
Perspective on Genome Organization in Nature Methods
March 2, 2020 — A perspective article on genome organization from the lab is out in Nature Method: https://www.nature.com/articles/s41592-020-0758-3
Preprint alert
January 1, 2020 ORP1L regulates dynein clustering on endolysosmal membranes in response to cholesterol levels by Thakur et al is out in bioRxiv: https://www.biorxiv.org/content/10.1101/2020.08.28.273037v5.abstract
NIH-NIGMS-RM1
The Lakadamyali lab is excited to receive a collaborative RM1 grant from NIH-NIGMS, together with the Ostap, Holzbaur, & Dominguez labs at UPenn, and the Vavylonis lab at Lehigh University! We will study the mechanisms of mitochondrial transport from atomistic to cell biological level.
Read MoreInstitute on Aging Pilot Grant
The Lakadamyali lab is excited to receive a pilot grant from the IOA at UPenn to study tau aggregation using super-resolution microscopy!
Read MoreCollaboration with Epstein Lab in eLife
Our collaborative work with the Epstein lab on the role of H3K9me2 on heterochromatin positioning is published in eLife. Congratulations to Andrey and all the co-authors.
NIH-NIGMS RO1
Melike receives an RO1 from the NIH-NIGMS for developing new methods for quantifying protein stoichiometry with super-resolution microscopy! Congratulations to the Lakadamyali lab for this great achievement!
NSF-EFRI-CEE Grant
Melike receives an NSF-EFRI-CEE grant together with Carlos Castro (Ohio State University), Michael Poirier (Ohio State University) and Laszlo Tora (IGBMC) to engineer new DNA-origami tools for visualizing and manipulating chromatin. Congratulations to the whole team and excited to officially kick off this exciting collaboration.
Welcome Angel - Visiting Student
We welcome Angel, a visiting student from the Cosma lab at CRG, Barcelona. Excited to have him here to do super-resolution imaging of chromatin remodeling in reprogramming!
Histone Tail Acetylation Impacting Chromatin Structure in Nucleic Acids Research
Check out our new paper on how histone tail acetylation impacts chromatin structure, published in Nucleic Acids Research.
Welcome Alex - Undergraduate Student
We welcome Alex Zhou from the Physics Department as a new undergraduate student in the Lakadamyali lab.
Invariant Quantification of Dynein Stoichiometry in Biophysical Journal
Lakadamyali lab publishes a paper on imaging invariant quantification of dynein stoichiometry in the Biophysical Journal!
Detyrosinated Microtubules in Autophagy in JCB
Congratulations to Nitin for publishing his paper on the role of detyrosinated microtubules in autophagy in JCB!
Linda Pechenik Montague Investigator Award
Melike receives a Linda Pechenik Montague Investigator Award. We are grateful to Laddie and Linda Pechenik for their generous donation that made this award possible and the Perelman School of Medicine for the great honor.
Farewell Nitin
We bid farewell to Nitin Mohan. We will miss Nitin and wish him the best as he starts his independent PI position at IIT-Kanpur.
Frequency Multiplexing Multicolor Imaging in PNAS
Lakadamyali lab’s new paper on multicolor imaging by frequency multiplexing is published in PNAS!
NSF Pilot Award
Melike receives an NSF Science and Technology Center for Engineering Mechano-Biology pilot award to study the role of nuclear lamina in chromatin organization.
NMDA Receptor Nanoorganization on Cover of Cell Reports
Our work on NMDA receptor nanoorganization is selected for the cover of Cell Reports!